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Vesicular Stomatitis Confirmed at Arizona Equine Premises
- December 31, 2025
- ⎯ EDCC Health Watch

On Oct. 31, the National Veterinary Services Laboratories confirmed findings of vesicular stomatitis New Jersey virus (VSNJV) in horses on two separate premises in Cochise County, Arizona. In November, two new cases were reported, including one case in Gila County and one in Santa Cruz County.
On Dec. 9, the National Veterinary Services Laboratories detected a new VSV case by PCR on swab samples from a lesioned wild horse from the Salt River Wild Horse Management Group located in the Tonto National Forest in Maricopa County.
Since then, one new affected equine premises has been identified in Santa Cruz County. Additionally, one previously affected premises in Santa Cruz County has been released from quarantine.
The last outbreak of VSV in the U.S. occurred from May 2023 through January 2024, affecting 319 premises across California, Nevada, and Texas. VSV circulates annually between livestock and insect vectors in southern Mexico and only occasionally results in incursion to the U.S.
EDCC Health Watch is an Equine Network marketing program that utilizes information from the Equine Disease Communication Center (EDCC) to create and disseminate verified equine disease reports. The EDCC is an independent nonprofit organization that is supported by industry donations in order to provide open access to infectious disease information.
About Vesicular Stomatitis
Vesicular stomatitis is a viral disease of horses, donkeys, mules, cattle, swine and New World camelids that occurs in the Western Hemisphere. It is named for the characteristic vesicular lesions it causes in the form of blisters, crusts and ulceration of the lips, muzzle, nose, tongue, ears, sheath, teats and/or coronary band. The virus is transmitted by biting midges and therefore is seasonal.
Clinical Signs for vesicular stomatitis include:
- Vesicle formation leading to ulcerative lesions on the lips, muzzle, nostrils and tongue. The tongue is often the most severely affected area.
- Ulceration of the inner surface of the lips.
- Crusting of the muzzle, nostrils, and/or inside the ears.
- Excessive salivation secondary to the oral lesions.
- Difficulty picking up and chewing feed.
- Lameness due to painful erosions on the coronary band.
- Lesions can occur on the udder, sheath and inside of the ear.
- Lesions can develop secondary infections resulting in slow-to-heal wounds.
- Animals on pastures are at increased risk of vesicular stomatitis.
Initial diagnosis is based on recognition of characteristic vesicular lesions. Infection is confirmed via laboratory testing for serum antibodies and/or virus identification in fluid samples from active lesions. Veterinarians are required to report suspected cases to state/federal animal health officials who will direct sample submission to an approved regulatory laboratory for diagnostic testing.
There is no specific treatment for vesicular stomatitis. Best practices include implementing good biosecurity and treating affected horses with pain relievers, anti-inflammatories and supportive care as recommended by a veterinarian.
Isolating all affected animals and placing the premise on immediate quarantine is required until all horses have fully recovered and no active lesions are present. The State Veterinarian will work with the local veterinarian to determine and implement necessary quarantine procedures.