Can a horse receive too many vaccinations? - The Horse Owner's Resource

Can a horse receive too many vaccinations?

If a horse’s history is unknown, it is best to follow protocols designed for unvaccinated animals.
Publish date:

Q:A few months ago, my husband and I took in a rescue horse, and we are slowly doing what we can to restore his health though careful re-feeding, farriery work and veterinary care. However there’s one area of his health that has me worried: We can’t find any information on which vaccinations this horse may or may not have received in his life. How do you handle vaccinations for horses with unknown histories? Which factors, such as a horse’s age, are relevant to this question? My gelding is about 9 years old and does not seem to have health problems beyond being malnourished and having been neglected Should we act as if he hasn’t had any vaccinations and “start from scratch?” Is there any harm in that approach? Or would it be better to have his blood analyzed to see if he has immunity from previous vaccinations and fill in any gaps?

Name withheld by request

A:In general, there is no harm, other than financial, in proceeding as if a horse had never been vaccinated previously. Indeed, when a horse’s vaccination history is unknown it is best to consider it naïve and use protocols designed for unvaccinated horses. Giving additional doses of most vaccines would neither enhance nor inhibit the horse’s ability to develop immunological memory, which is the goal of vaccination.

The one notable exception is the strangles vaccine. In rare cases, horses who have previously contracted strangles---or have been repeatedly vaccinated against the disease---may develop a potentially serious complication known as
purpura hemorrhagica.

Characterized by swelling of the blood vessels, usually of the head, legs and abdomen, purpura hemorrhagica results from an abnormal immune reaction. Although the risk of this condition is small, it is best to draw a titer to determine whether a horse carries antibodies to the causal organism (Streptococcus equi) before scheduling a strangles vaccination.

David W. Horohov, PhD

Director, Maxwell H. Gluck

Equine Research Center

University of Kentucky

Lexington, Kentucky