Free Online Research Paper Collection Covers Equine Antimicrobial Resistance

Credit: National Institutes of Health | National Institute of Allergy and Infectious Diseases (NIAID) image library Scanning electron micrograph of methicillin-resistant Staphylococcus aureus (MRSA, brown) surrounded by cellular debris. MRSA resists treatment with many antimicrobial medications.

It’s World Antimicrobial Awareness Week.

The Equine Veterinary Journal (EVJ) has released its Antimicrobial Resistance Virtual Issue, a special online collection of articles on antimicrobial medication resistance. The collection is free to all readers and highlights the current understanding of equine antimicrobial resistance and how the veterinary profession can preserve the effectiveness of these essential medicines.

Antimicrobial resistance is an emerging clinical problem, recognized internationally as one of the largest threats to human and animal health. All major health and veterinary organizations are working to limit the development of resistance so that effective antimicrobials can be retained for use in clinical practice.

Following the launch of the British Equine Veterinary Association’s (BEVA) PROTECT ME campaign in 2012, two-thirds of equine practices in Britain now adhere to self-imposed policies governing the responsible use of antimicrobials. The BEVA Protect ME toolkit, which includes posters, fact sheets and light-hearted comic strips for BEVA members to share with their clients at the surgery or through social media, can be downloaded at

Incisional infection is a chronic complication of colic surgery.

The Equine Veterinary Journal (EVJ) was the first publication worldwide to adopt an antimicrobial stewardship policy in its author guidelines.

The new online collection comprises ten clinical reports and studies and three editorials covering current trends on bacterial populations, risk factors and the appropriate use of antimicrobials in practice.

A clinical report on the changes in bacterial populations in foals with sepsis raises the question whether the emergence of resistance in horses has occurred as a result of antibiotic use in humans, with nosocomial spread from human handlers in foals.

 Studies on the prevalence of fecal carriage of antimicrobial resistant E. coli show its prevalence to be common in normal horses in the community in the UK, although MRSA carriage was rare. Data suggested transmission of resistant bacteria from animals receiving antibiotics may result in carriage of bacteria by in-contact animals.

Many horses will have a discharge from the incision after colic surgery.

The need for judicious use of antimicrobials is reinforced in a study on antimicrobial-associated diarrhea in three equine referral practices. Two papers investigate both prescribing practice in the UK and the impact of antimicrobial use on infection and pyrexia in hospitalized horses, concluding that there are opportunities for more targeted, ‘smart’ use antimicrobials in the perioperative period, rather than simply more antimicrobials.

The final study discusses a low-cost syndromic surveillance model for monitoring healthcare associated infection in clinical practice to provide a realistic benchmark against which other hospitals may compare antimicrobial study data.

Three supporting editorials complete the online collection, giving important comment on the overall situation of antimicrobial resistance in horses, including the current political situation and antimicrobials and surgical site infection.

Professor Peter Clegg, Associate Editor of the Equine Veterinary Journal said: “It remains to be determined how big a problem antimicrobial resistance will become for the equine veterinary profession, either through greater difficulties in treating horses, or through political pressure to restrict access to antimicrobials. Meanwhile the EVJ remains committed to the promotion of responsible stewardship to best preserve the efficacy of the drugs we have got for as long as we can.”

Mark Bowen, President of the British Equine Veterinary Association and guest editor said: “BEVA has a long-term commitment to promoting responsible antimicrobial use throughout the profession. The work of the equine profession in preserving the highest priority antimicrobials will ensure efficacy can be retained for as long as is possible.”

The antimicrobial online collection is available free online at:

This article is based on a news release.




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